Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4477428 | 0.87 | CNR2 (0.64) | CNR2NR1H2NR1H3P2RX7LMNA | |
| SCHEMBL4651372 | 0.87 | CNR2 (0.51) | CNR2RORCLMNAPOLBHTT | |
| SCHEMBL4472224 | 0.81 | CNR2 (0.66) | CNR2P2RX7LMNAPOLBS1PR1 | |
| SCHEMBL4476258 | 0.80 | CNR2 (0.58) | CNR2P2RX7S1PR1S1PR5 | |
| SCHEMBL4481910 | 0.79 | CNR2 (0.61) | CNR2P2RX7S1PR1S1PR5HTT | |
| SCHEMBL4466232 | 0.79 | CNR2 (0.61) | CNR2NR1H2NR1H3LMNAPOLB | |
| SCHEMBL4651291 | 0.79 | CNR2 (0.56) | CNR2LMNAPOLBS1PR1S1PR5 | |
| SCHEMBL14495607 | 0.78 | CNR2 (0.63) | CNR2LMNAPOLBS1PR1S1PR5 | |
| SCHEMBL4482477 | 0.78 | CNR2 (0.63) | CNR2LMNAPOLBS1PR1S1PR5 | |
| SCHEMBL4473174 | 0.77 | CNR2 (0.59) | CNR2NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |