Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 13/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | THPO | P40225 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650998 | 0.88 | SCNN1A (0.33) | SCNN1AALDH1A1HSD17B10KDM4EHPGD | |
| Trifluoroacetic Acid SCHEMBL3527475 | 0.80 | SCNN1A (0.43) | SCNN1AALDH1A1HSD17B10KDM4EHPGD | |
| Trifluoroacetic Acid SCHEMBL3527480 | 0.77 | SCNN1A (0.46) | SCNN1AALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL27709814 | 0.73 | SCNN1A (0.52) | SCNN1AALDH1A1HSD17B10KDM4EHPGD | |
| Bromide SCHEMBL4693421 | 0.73 | SCNN1A (0.44) | SCNN1AALDH1A1HSD17B10KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL4693835 | 0.72 | KDM4E (0.46) | SCNN1AALDH1A1HSD17B10KDM4EHPGD | |
| Bromide SCHEMBL4789642 | 0.72 | SCNN1A (0.43) | SCNN1AALDH1A1HSD17B10KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL4415210 | 0.71 | KDM4E (0.39) | SCNN1AALDH1A1HSD17B10KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL4415671 | 0.71 | KDM4E (0.39) | SCNN1AALDH1A1HSD17B10KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL6013443 | 0.71 | KDM4E (0.39) | SCNN1AALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968969-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007071396-A2 | PYRAZINOYLGUANIDINE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY OR ALLERGIC CONDITIONS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |