SCHEMBL4650902

SCHEMBL4650902

C=CCC(C)(C(=O)c1ccc(N2CCOCC2)cc1)N(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.46
MAPT P10636 13/20 0.44
LMNA P02545 4/20 0.44
SMN1; SMN2 Q16637 6/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPK1 P28482 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
ATM Q13315 1/20 0.41
MAOB P27338 1/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
ALDH1A1 P00352 6/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
PTPN1 P18031 1/20 0.40
HPGD P15428 2/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4819053 0.86 GSK3B (0.47) GSK3BMAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL8899929 0.84 MAPT (0.44) GSK3BMAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL4650579 0.83 GSK3B (0.44) GSK3BMAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL7946230 0.82 GSK3B (0.43) GSK3BMAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL8898186 0.82 GSK3B (0.43) GSK3BMAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL8898770 0.81 GSK3B (0.47) GSK3BMAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL8898928 0.81 MAPT (0.44) GSK3BMAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL2774235 0.80 SMN1; SMN2 (0.50) GSK3BMAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL8899177 0.79 SMN1; SMN2 (0.45) GSK3BMAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL308691 0.79 MAPT (0.52) GSK3BMAPTLMNASMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264930-B1 Cellulose fibers comprising radiation activatable resins PROCTER & GAMBLE (US) 2008-09-17 EP disclosed
US-7365104-B2 Light curable articles containing azinium salts EASTMAN KODAK COMPANY (US) 2008-04-29 US disclosed
US-20060223902-A1 Light curable articles containing azinium salts EASTMAN KODAK COMPANY 2006-10-05 US disclosed
US-6887347-B2 Cellulose fibers comprising radiation activatable resin formalities THE PROCTER AND GAMBLE COMPANY (US) 2005-05-03 US disclosed
US-20040140070-A1 Cellulose fibers comprising radiation activatable resin formalities THE PROCTER & GAMBLE COMPANY 2004-07-22 US disclosed
WO-2002101139-A1 CELLULOSE FIBERS COMPRISING RADIATION ACTIVATABLE RESINS THE PROCTER & GAMBLE COMPANY (US) 2002-12-19 WO disclosed
EP-1264930-A1 Cellulose fibers comprising radiation activatable resins THE PROCTER & GAMBLE COMPANY (US) 2002-12-11 EP disclosed
US-6242057-B1 GENERATING PHOTOINITIATORS KIMBERLY-CLARK WORLDWIDE, INC. 2001-06-05 US disclosed
EP-0767803-B1 METHOD OF GENERATING A REACTIVE SPECIES AND APPLICATIONS THEREFOR KIMBERLY CLARK CO (US) 2000-08-23 EP disclosed
US-6090236-A POLYMERIC WEB COATED WITH IRRADIATION-CURED RESIN PHOTOINITIATED WITH PHOTOINITIATOR HAVING A COVALENTLY BOUND SENSITIZING MOIETY SPECIFIC TO WAVELENGTH OF CURING RADIATION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-07-18 US disclosed
US-5686503-A PHOTOINITIATORS KIMBERLY-CLARK CORPORATION (US) 1997-11-11 US disclosed
US-5685754-A FIBERS, WEBS, PHOTOSENSITIZER AND PHOTOINITIATOR COVALENTLY BONDED AS A PHOTOREACTOR KIMBERLY-CLARK CORPORATION (US) 1997-11-11 US disclosed
US-5629356-A PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE CIBA GEIGY CORPORATION (US) 1997-05-13 US disclosed
EP-0767803-A1 METHOD OF GENERATING A REACTIVE SPECIES AND APPLICATIONS THEREFOR KIMBERLY-CLARK CORPORATION (US) 1997-04-16 EP disclosed
US-5554663-A α-aminoacetophenones as photoinitiators CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5534629-A PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
WO-1996000740-A1 METHOD OF GENERATING A REACTIVE SPECIES AND APPLICATIONS THEREFOR KIMBERLY-CLARK CORPORATION (US) 1996-01-11 WO disclosed
EP-0284561-B1 ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS CIBA-GEIGY AG (CH) 1993-05-12 EP disclosed
US-5077402-A For photocuring pigmented systems; printing inks, lacquers CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
EP-0284561-A2 Alpha-aminoacetophenones as photo initiators CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed