Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647422 | 0.88 | — | — | |
| SCHEMBL9766521 | 0.75 | SLC6A2 (0.37) | HTR2AHTR2CSMN1; SMN2USP2 | |
| SCHEMBL4025607 | 0.71 | — | — | |
| SCHEMBL7741975 | 0.71 | — | — | |
| SCHEMBL6797745 | 0.71 | — | — | |
| SCHEMBL19474284 | 0.69 | — | — | |
| SCHEMBL8662458 | 0.68 | — | — | |
| SCHEMBL7256913 | 0.68 | CDK1 (0.32) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL15355111 | 0.68 | NPSR1 (0.40) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL4274460 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426768-B1 | Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases | UCB PHARMA SA (BE) | 2008-09-17 | — | — | EP | disclosed |
| EP-1426768-A2 | Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases | UCB S.A. (BE) | 2004-06-09 | — | — | EP | disclosed |