Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652663 | 1.00 | HTT (0.59) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL4651512 | 1.00 | HTT (0.59) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL4652666 | 1.00 | HTT (0.59) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL4653712 | 1.00 | HTT (0.59) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL4653715 | 1.00 | HTT (0.59) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL17625202 | 0.96 | HTT (0.62) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL4651469 | 0.91 | HTT (0.58) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL29198064 | 0.91 | HTT (0.58) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL29198061 | 0.91 | HTT (0.58) | HTTPOLBAPEX1TDP1KDM4E | |
| SCHEMBL29198062 | 0.91 | HTT (0.58) | HTTPOLBAPEX1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975687-A1 | Method of uniform and defect free liquid crystal aligning layers | Rolic AG (CH) | 2008-10-01 | — | — | EP | disclosed |