Perfosfamide

Perfosfamide

SCHEMBL4652

O=[P@]1(N(CCCl)CCCl)N[C@H](OO)CCO1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.49
KDM4E B2RXH2 1/20 0.48
ALOX15 P16050 1/20 0.48
MAPK1 P28482 1/20 0.48
CRYZ Q08257 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perfosfamide SCHEMBL1650261 1.00 NPSR1 (0.49) NPSR1KDM4EALOX15MAPK1CRYZ
Perfosfamide SCHEMBL28131626 0.95 NPSR1 (0.48) NPSR1KDM4EALOX15MAPK1CRYZ
Perfosfamide SCHEMBL5089114 0.91 NPSR1 (0.66) NPSR1KDM4EALOX15MAPK1CRYZ
Perfosfamide SCHEMBL28091536 0.90 NPSR1 (0.44) NPSR1KDM4EALOX15MAPK1CRYZ
Perfosfamide SCHEMBL28091534 0.90 NPSR1 (0.44) NPSR1KDM4EALOX15MAPK1CRYZ
SCHEMBL10412920 0.85 NPSR1 (0.53) NPSR1KDM4EALOX15MAPK1CRYZ
Pipobroman SCHEMBL27849441 0.84 KDM4E (0.38) NPSR1KDM4EALOX15MAPK1CRYZ
Pipobroman SCHEMBL7100695 0.84 KDM4E (0.38) NPSR1KDM4EALOX15MAPK1CRYZ
SCHEMBL10413698 0.83 NPSR1 (0.47) NPSR1KDM4EALOX15MAPK1CRYZ
SCHEMBL17897647 0.82 NPSR1 (0.46) NPSR1KDM4EALOX15MAPK1CRYZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12824 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
EP-4729063-A2 TREATMENT OF CANCER USING COENZYME Q10 COMBINATION THERAPIES BPGbio, Inc. (US) 2026-04-22 EP claimed
US-12522572-B2 Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-01-13 US claimed
EP-4120980-B1 METHOD FOR WRAPPING A SANITARY ITEM OR A STACK COMPRISING A NUMBER OF SANITARY ITEMS BW CONVERTING GMBH (DE) 2025-10-22 EP claimed
US-12448559-B1 Puddle job with delayed setting of resin via a polymerization reaction with an activator HALLIBURTON ENERGY SERVICES, INC. (US) 2025-10-21 US claimed
EP-4602049-A1 SOS1 INHIBITORS Bayer Aktiengesellschaft (DE) 2025-08-20 EP claimed
EP-4587439-A1 SULFONE-SUBSTITUTED PYRIDO[3,4-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF CANCER Bayer Aktiengesellschaft (DE) 2025-07-23 EP claimed
US-20250154170-A1 FUSED PYRIMIDINES AS KRAS INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2025-05-15 US claimed
EP-4524131-A1 SMALL MOLECULES FOR TREATING CANCER, INHABITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH AlonBio Ltd. (IL) 2025-03-19 EP claimed
WO-2025021997-A1 NEW MAP4K1 INHIBITORS Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2025-01-30 WO claimed
CN-1679947-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1660438-A Slow released anticancer combination of medication embedded the interior of the body LANJIN BIOLOG ENGINEERING CO L (CN) 2005-08-31 CN claimed
US-20040092583-A1 Treatment for inhibiting neoplastic lesions SHANAHAN-PRENDERGAST ELIZABETH (IE) 2004-05-13 US claimed
EP-1351678-A2 TREATMENT FOR INHIBITING NEOPLASTIC LESIONS USING INCENSOLE AND/OR FURANOGERMACRENS Shanahan-Prendergast, Elizabeth (IE) 2003-10-15 EP claimed
US-6482802-B1 Use of neomycin for treating angiogenesis-related diseases ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. 2002-11-19 US claimed
EP-1083896-A4 USE OF NEOMYCIN FOR TREATING ANGIOGENESIS-RELATED DISEASES ENDOWMENT FOR RES IN HUMAN BIO (US) 2002-09-11 EP claimed
WO-2002053138-A2 TREATMENT FOR INHIBITING NEOPLASTIC LESIONS USING INCENSOLE AND/OR FURANOGERMACRENS SHANAHAN-PRENDERGAST ELISABETH (IE) 2002-07-11 WO claimed
EP-1083896-A1 USE OF NEOMYCIN FOR TREATING ANGIOGENESIS-RELATED DISEASES THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) 2001-03-21 EP claimed
WO-1999058126-B1 USE OF NEOMYCIN FOR TREATING ANGIOGENESIS-RELATED DISEASES ENDOWMENT RES INHUMAN BIOLOGY (US) 2000-02-17 WO claimed
WO-1999058126-A1 USE OF NEOMYCIN FOR TREATING ANGIOGENESIS-RELATED DISEASES THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) 1999-11-18 WO claimed