SCHEMBL4652465

SCHEMBL4652465

NCCCC(C(=O)[C@@H](N)CCC(=O)O)[C@H](N)C=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
GSR P00390 2/20 0.43
GRM8 O00222 1/20 0.43
GRM6 O15303 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIK1 P39086 1/20 0.43
GRM5 P41594 1/20 0.43
GRIA1 P42261 1/20 0.43
GRIA2 P42262 1/20 0.43
GRIA3 P42263 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
GRIA4 P48058 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIK2 Q13002 1/20 0.43
GRIK3 Q13003 1/20 0.43
GRIN2B Q13224 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7147106 0.81 GSR (0.50) CYP1A2GSRGRM8GRM6GRIN2D
SCHEMBL7147101 0.81 GSR (0.50) CYP1A2GSRGRM8GRM6GRIN2D
SCHEMBL27182543 0.79 GSR (0.56) CYP1A2GSRGRM8GRM6GRIN2D
SCHEMBL4412274 0.73 CYP1A2 (0.48) CYP1A2GSRGRM8GRM6GRIN2D
Glutamic Acid SCHEMBL6850406 0.72 GSR (0.75) CYP1A2GSRGRM8GRM6GRIN2D
SCHEMBL5074626 0.72 CYP1A2 (0.56) CYP1A2GSRGRM8GRM6GRIN2D
D-Glutamate SCHEMBL11310231 0.72 GSR (0.75) CYP1A2GSRGRM8GRM6GRIN2D
D-Glutamate SCHEMBL4414452 0.72 GSR (0.75) CYP1A2GSRGRM8GRM6GRIN2D
Glutamic Acid SCHEMBL2153076 0.72 GSR (0.75) CYP1A2GSRGRM8GRM6GRIN2D
D-Glutamate SCHEMBL6850403 0.72 GSR (0.75) CYP1A2GSRGRM8GRM6GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1613369-A4 COMPOSITIONS AND METHODS FOR DELIVERING THYMOSIN BETA 4, ANALOGUES, ISOFORMS AND OTHER DERIVATIVES REGENERX BIOPHARMACEUTICALS (US) 2008-10-01 EP disclosed
EP-1613369-A2 COMPOSITIONS AND METHODS FOR DELIVERING THYMOSIN BETA 4, ANALOGUES, ISOFORMS AND OTHER DERIVATIVES Regenerx Biopharmaceuticals, Inc. (US) 2006-01-11 EP disclosed
US-6919076-B1 Conjugates of agents and transglutaminase substrate linking molecules PERICOR SCIENCE, INC. (US) 2005-07-19 US disclosed
WO-2004091550-A2 COMPOSITIONS AND METHODS FOR DELIVERING THYMOSIN BETA 4, ANALOGUES, ISOFORMS AND OTHER DERIVATIVES REGENERX BIOPHARMACEUTICALS, INC. (US) 2004-10-28 WO disclosed