Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | PER2 | O15055 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30697352 | 0.98 | PIK3CD (0.51) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28740068 | 0.98 | PIK3CD (0.51) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| Bromide SCHEMBL27981325 | 0.96 | PIK3CD (0.50) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL20894928 | 0.94 | PIK3CD (0.55) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| Acetic Acid SCHEMBL29252348 | 0.91 | GBA1 (0.46) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15560788 | 0.89 | GBA1 (0.43) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29252569 | 0.89 | GBA1 (0.44) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL20894926 | 0.86 | PIK3CD (0.58) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28354948 | 0.86 | GBA1 (0.44) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| Trifluoromethanesulfonic Acid SCHEMBL29252133 | 0.85 | GBA1 (0.42) | PIK3CDCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606253-A4 | PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEUVLINIC ACID ESTERS WITH NITRO COMPOUNDS | DU PONT (US) | 2008-03-05 | — | — | EP | disclosed |
| EP-1606253-A1 | PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEUVLINIC ACID ESTERS WITH NITRO COMPOUNDS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004085390-A1 | PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEUVLINIC ACID ESTERS WITH NITRO COMPOUNDS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2004-10-07 | — | — | WO | disclosed |