Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | SHBG | P04278 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654508 | 0.98 | PPARA (0.71) | PPARAKDM4EHTTKAT8ESR1 | |
| SCHEMBL4655436 | 0.98 | PPARA (0.71) | PPARAKDM4EHTTKAT8ESR1 | |
| SCHEMBL4653153 | 0.98 | PPARA (0.71) | PPARAKDM4EHTTKAT8ESR1 | |
| SCHEMBL4654357 | 0.98 | PPARA (0.71) | PPARAKDM4EHTTKAT8ESR1 | |
| SCHEMBL4654500 | 0.98 | PPARA (0.71) | PPARAKDM4EHTTKAT8ESR1 | |
| SCHEMBL4654281 | 0.98 | PPARA (0.71) | PPARAKDM4EHTTKAT8ESR1 | |
| SCHEMBL4654279 | 0.98 | PPARA (0.71) | PPARAKDM4EHTTKAT8ESR1 | |
| SCHEMBL4653191 | 0.95 | PPARA (0.61) | PPARAKDM4EHTTKAT8ESR1 | |
| SCHEMBL29189686 | 0.92 | PPARA (0.79) | PPARAKDM4EKAT8ESR1ADRA2A | |
| SCHEMBL5160191 | 0.92 | PPARA (0.79) | PPARAKDM4EKAT8ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2746822-B1 | PLASTIC LENS | HOYA CORP (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-8895661-B2 | Plastic lens | HOYA CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| EP-2746822-A1 | PLASTIC LENS | HOYA CORPORATION (JP) | 2014-06-25 | — | — | EP | disclosed |
| EP-1505412-B1 | Plastic lens and process for producing the lens | HOYA CORP (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-20070141355-A1 | Plastic lens and process for preparing the lens | HOYA CORPORATION | 2007-06-21 | — | — | US | disclosed |
| US-20050046967-A1 | Plastic lens and process for preparing the lens | HOYA CORPORATION (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1505412-A1 | Plastic lens and process for producing the lens | HOYA CORPORATION (JP) | 2005-02-09 | — | — | EP | disclosed |