Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28691594 | 0.87 | EPHX2 (0.48) | KMT2AEPHX2RAB9AALDH1A1HTT | |
| SCHEMBL16256817 | 0.85 | KMT2A (0.52) | KMT2AEPHX2CASP3 | |
| SCHEMBL3177417 | 0.85 | KMT2A (0.62) | KMT2AEPHX2CASP3 | |
| SCHEMBL31652901 | 0.84 | KMT2A (0.56) | KMT2AEPHX2CASP3EPHX1 | |
| SCHEMBL2744319 | 0.84 | KMT2A (0.55) | KMT2AEPHX2CASP3EPHX1 | |
| SCHEMBL24864773 | 0.83 | KMT2A (0.52) | KMT2AEPHX2CASP3EPHX1 | |
| SCHEMBL27644637 | 0.83 | EPHX2 (0.59) | KMT2AEPHX2NPC1RAB9ACASP3 | |
| SCHEMBL693419 | 0.83 | KMT2A (0.52) | KMT2AEPHX2CASP3EPHX1 | |
| SCHEMBL31010055 | 0.83 | KMT2A (0.55) | KMT2AEPHX2CASP3 | |
| SCHEMBL2057615 | 0.83 | KMT2A (0.55) | KMT2AEPHX2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706154-A4 | IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO SPA (IT) | 2008-11-26 | — | — | EP | disclosed |
| EP-1706154-A1 | IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS | Bracco Imaging, S.P.A. (IT) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005067983-A1 | IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2005-07-28 | — | — | WO | disclosed |