⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639026 | 0.77 | — | — | |
| SCHEMBL4655762 | 0.74 | — | — | |
| SCHEMBL10473344 | 0.74 | — | — | |
| SCHEMBL19558957 | 0.72 | — | — | |
| SCHEMBL8983086 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL9696828 | 0.70 | — | — | |
| SCHEMBL11148888 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL27238411 | 0.67 | — | — | |
| SCHEMBL9416852 | 0.67 | TP53 (0.33) | — | |
| SCHEMBL30320251 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813644-A | Preparation method of flomoxef mother nucleus | 广东立国制药有限公司 | 2023-09-29 | — | — | CN | disclosed |
| EP-1996595-A2 | PROCESS FOR THE PREPARATION OF (1-OXA- OR l-THIA-)3- CEPHEM DERIVATIVES AND RELATED INTERMEDIATES | CARTHESIA s.a.s. DI EMANUELA MIGLIAVACCA & C. (IT) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007105253-A2 | PREPARATION OF (1-OXA- OR l-THIA-)3- CEPHEM DERIVATIVES | CARTHESIA S.A.S. DI EMANUELA MIGLIAVACCA & C. (IT) | 2007-09-20 | — | — | WO | disclosed |
| EP-0416410-B1 | Piperaziniocephalosporins | SHIONOGI & CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| EP-0191989-B1 | ANTIBIOTIC ISOXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-5143910-A | PIPERAZINIOCEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0367124-A1 | Penicillanic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-05-09 | — | — | EP | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4912224-A | Containing a aminothiazolyl or aminothiadiazolyl ring | SHIONOGI & CO., LTD. (JP) | 1990-03-27 | — | — | US | disclosed |
| US-4897489-A | 2-/5-OXO-2-TETRAHYDROFURANY4-3-OXOISOXOL-IDINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0128536-B1 | FLUOROMETHYLTHIOOXACEPHALOSPORIN DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4748170-A | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4634697-A | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1987-01-06 | — | — | US | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |
| US-4532233-A | Antibiotics | SHIONOGI & CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| EP-0136721-A2 | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1985-04-10 | — | — | EP | disclosed |
| US-4491547-A | Fluoromethylthioacetic acid compounds | SHIONOGI & CO., LTD. (JP) | 1985-01-01 | — | — | US | disclosed |
| EP-0128536-A1 | Fluoromethylthiooxacephalosporin derivatives | SHIONOGI & CO., LTD. (JP) | 1984-12-19 | — | — | EP | disclosed |