SCHEMBL465537

SCHEMBL465537

CCCCC(CC)COC(=O)CS.C[Sn]

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.68
TSHR P16473 3/20 0.68
TDP1 Q9NUW8 2/20 0.68
ATM Q13315 1/20 0.68
RECQL P46063 1/20 0.56
ALDH1A1 P00352 7/20 0.51
CA2 P00918 4/20 0.51
LMNA P02545 4/20 0.47
MAPK1 P28482 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP14 P50281 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5702384 1.00 CYP3A4 (0.68) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL27210 0.97 CYP3A4 (0.72) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL7639807 0.95 CYP3A4 (0.70) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL962909 0.95 CYP3A4 (0.70) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL10579397 0.95 CYP3A4 (0.70) CYP3A4TSHRTDP1ATMRECQL
Hydrogen Sulfide SCHEMBL7193596 0.95 CYP3A4 (0.70) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL10796442 0.95 CYP3A4 (0.70) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL17889800 0.93 CYP3A4 (0.68) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL16447750 0.93 CYP3A4 (0.68) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL4457581 0.92 CYP3A4 (0.62) CYP3A4TSHRTDP1ATMRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2785790-B1 STABILIZED COMPOSITIONS OF HALOGENATED POLYMERS ROHM & HAAS (US) 2017-02-01 EP claimed
US-20140336316-A1 STABILIZED POLYMER COMPOSITIONS ROHM & HAAS (US) 2014-11-13 US claimed
EP-2785790-A1 STABILIZED COMPOSITIONS OF HALOGENATED POLYMERS Rohm and Haas Company (US) 2014-10-08 EP claimed
US-8614268-B2 Stabilized polymer compositions ROHM AND HAAS COMPANY (US) 2013-12-24 US claimed
WO-2013085714-A1 STABILIZED COMPOSITIONS OF HALOGENATED POLYMERS ROHM AND HAAS COMPANY (US) 2013-06-13 WO claimed
EP-2241596-B1 Stabilized polymer compositions ROHM & HAAS (US) 2011-11-23 EP claimed
EP-2241595-B1 Stabilized polymer compositions ROHM & HAAS (US) 2011-09-21 EP claimed
US-20100267873-A1 Stabilized polymer compositions ROHM AND HAAS COMPANY 2010-10-21 US claimed
US-20100267872-A1 Stabilized polymer compositions ROHM AND HAAS COMPANY 2010-10-21 US claimed
EP-2241595-A1 Stabilized polymer compositions Rohm and Haas Company (US) 2010-10-20 EP claimed
EP-2241596-A1 Stabilized polymer compositions Rohm and Haas Company (US) 2010-10-20 EP claimed
EP-3030610-B1 HEAT STABILIZER FOR HALOGEN-CONTAINING POLYMERS GALATA CHEMICALS LLC (US) 2017-05-17 EP disclosed
US-9587088-B2 Heat stabilizer for halogen-containing polymers GALATA CHEMICALS LLC (US) 2017-03-07 US disclosed
EP-2785790-B1 STABILIZED COMPOSITIONS OF HALOGENATED POLYMERS ROHM & HAAS (US) 2017-02-01 EP disclosed
WO-2016147150-A1 RIGID POLYVINYLCHLORIDE COMPOSITIONS FOR SHRINK FILMS FOR USE IN LPG CYLINDER TAMPER EVIDENT SEALS LPG EQUIPMENT RESEARCH CENTRE (IN) 2016-09-22 WO disclosed
EP-2298835-A1 Stabilized polymer compositions ROHM AND HAAS COMPANY (US) 2011-03-23 EP disclosed
US-20100267873-A1 Stabilized polymer compositions ROHM AND HAAS COMPANY 2010-10-21 US disclosed
US-20100267872-A1 Stabilized polymer compositions ROHM AND HAAS COMPANY 2010-10-21 US disclosed
EP-2241595-A1 Stabilized polymer compositions Rohm and Haas Company (US) 2010-10-20 EP disclosed
EP-2241596-A1 Stabilized polymer compositions Rohm and Haas Company (US) 2010-10-20 EP disclosed