Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 14/20 | 0.61 |
| ▸ | RARB | P10826 | 6/20 | 0.61 |
| ▸ | RARA | P10276 | 5/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957537 | 0.90 | RARG (0.76) | RARGRARBRARA | |
| SCHEMBL957366 | 0.89 | RARG (0.75) | RARGRARBRARA | |
| SCHEMBL4654752 | 0.84 | RARG (0.61) | RARGRARBRARAKDM4EALDH1A1 | |
| SCHEMBL4653856 | 0.83 | RARG (0.64) | RARGRARBRARA | |
| SCHEMBL4654649 | 0.83 | RARG (0.62) | RARGRARBRARA | |
| SCHEMBL4653506 | 0.83 | RARG (0.62) | RARGRARBRARA | |
| SCHEMBL4653528 | 0.83 | RARG (0.62) | RARGRARBRARA | |
| SCHEMBL4654747 | 0.82 | RARG (0.61) | RARGRARBRARA | |
| SCHEMBL7793753 | 0.82 | RARG (0.64) | RARGRARBRARA | |
| SCHEMBL4654765 | 0.80 | RARG (0.59) | RARGRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692093-B1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2008-11-19 | — | — | EP | claimed |