Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 16/20 | 0.56 |
| ▸ | RARB | P10826 | 7/20 | 0.56 |
| ▸ | RARA | P10276 | 6/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655897 | 0.91 | RARG (0.58) | RARGRARBRARANPSR1ALDH1A1 | |
| SCHEMBL4654752 | 0.90 | RARG (0.61) | RARGRARBRARANPSR1ALDH1A1 | |
| SCHEMBL4653964 | 0.90 | RARG (0.55) | RARGRARBRARANPSR1ALDH1A1 | |
| SCHEMBL4653634 | 0.90 | RARG (0.56) | RARGRARBRARANPSR1ALDH1A1 | |
| SCHEMBL957262 | 0.90 | RARG (0.66) | RARGRARBRARANPSR1ALDH1A1 | |
| SCHEMBL4654642 | 0.89 | RARG (0.55) | RARGRARBRARANPSR1ALDH1A1 | |
| SCHEMBL4654669 | 0.87 | RARG (0.55) | RARGRARBRARANPSR1ALDH1A1 | |
| SCHEMBL4655852 | 0.86 | RARG (0.54) | RARGRARBRARANPSR1ALDH1A1 | |
| SCHEMBL955172 | 0.86 | RARG (0.68) | RARGRARBRARANPSR1 | |
| SCHEMBL4653486 | 0.86 | RARG (0.54) | RARGRARBRARANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692093-B1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2008-11-19 | — | — | EP | claimed |