Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CES2 | O00748 | 4/20 | 0.67 |
| ▸ | CES1 | P23141 | 4/20 | 0.67 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nonanoate SCHEMBL9296766 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Undecanoate SCHEMBL5857955 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Stearic Acid SCHEMBL935 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Heptanoate SCHEMBL267659 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Stearic Acid SCHEMBL1543060 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Pentadecanoic Acid SCHEMBL18429968 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Myristic Acid SCHEMBL8003084 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Arachidic Acid SCHEMBL11867584 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Stearic Acid SCHEMBL5694020 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Palmitic Acid SCHEMBL103017 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111172765-B | Treating agent for polyurethane elastic fiber, method for treating polyurethane elastic fiber, and polyurethane elastic fiber | 竹本油脂株式会社 | 2020-10-27 | — | — | CN | disclosed |
| CN-111172765-A | Treating agent for polyurethane elastic fiber, method for treating polyurethane elastic fiber, and polyurethane elastic fiber | 竹本油脂株式会社 | 2020-05-19 | — | — | CN | disclosed |
| EP-1663165-B1 | IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF | MALLINCKRODT INC (US) | 2008-12-03 | — | — | EP | disclosed |
| US-7456306-B2 | Stearate composition and method of production thereof | MALLINCKRODT INC (US) | 2008-11-25 | — | — | US | disclosed |
| US-20080200358-A1 | Oiling Agent for Fiber Treatment | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2008-08-21 | — | — | US | disclosed |
| US-7385068-B2 | Stearate composition and method | MALLINCKRODT INC. (US) | 2008-06-10 | — | — | US | disclosed |
| EP-1781259-A2 | IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF | MALLINCKRODT, INC. (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20060281937-A1 | Stearate composition and method | SpecGx LLC | 2006-12-14 | — | — | US | disclosed |
| US-20060247456-A1 | Stearate composition and method of production thereof | SpecGx LLC | 2006-11-02 | — | — | US | disclosed |
| EP-1663165-A2 | IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF | MALLINCKRODT, INC. (US) | 2006-06-07 | — | — | EP | disclosed |
| EP-0900876-B1 | TREATMENT FOR ELASTIC POLYURETHANE FIBERS, AND ELASTIC POLYURETHANE FIBERS TREATED THEREWITH | TAKEMOTO OIL & FAT CO LTD (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2006023035-A2 | IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF | MALLINCKRODT INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20050228089-A1 | Lubricant for treating elastic fiber | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
| WO-2005011641-A2 | IMPROVED STEARATE COMPOSITION AND METHOD OF PRODUCTION THEREOF | MALLINCKRODT, INC. (US) | 2005-02-10 | — | — | WO | disclosed |
| US-6652599-B1 | Higher fatty acid magnesium salt colloidally dispersed in a silicone oil and an amino-modified silicone dispersant and an organic carboxylic acid; excellent winding form, decrease in deposition and accumulation of scum on guides during process | TAKEMOTO OIL & FAT CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |
| US-6171516-B1 | CONTAINING MODIFIED SILICONE OIL AND FATTY ACID MAGNESIUM SALT | TAKEMOTO OIL & FAT CO., LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0900876-A1 | TREATMENT FOR ELASTIC POLYURETHANE FIBERS, AND ELASTIC POLYURETHANE FIBERS TREATED THEREWITH | TAKEMOTO OIL & FAT CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |