SCHEMBL465598

SCHEMBL465598

O=[C]C(F)(F)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2466 0.70
SCHEMBL855112 0.70
SCHEMBL10580772 0.67
SCHEMBL8627911 0.67
SCHEMBL5860210 0.67
SCHEMBL7161927 0.67
SCHEMBL5456193 0.67
SCHEMBL7745891 0.67
SCHEMBL2201803 0.67
SCHEMBL19810558 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107382910-B Difluoromethyl aldehyde hydrazone compound and preparation method thereof 辽宁石油化工大学 2020-05-19 CN claimed
EP-2755983-B1 SUBSTITUTED CARBONYLOXYMETHYLPHOSPHORAMIDATE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS IDENIX PHARMACEUTICALS LLC (US) 2017-03-15 EP claimed
US-9403863-B2 Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections IDENIX PHARMACEUTICALS LLC (US) 2016-08-02 US claimed
WO-2024112705-A1 BORONIC ACID AND BORONATE COMPOSITIONS AND METHODS ELIMA THERAPEUTICS, INC. (US) 2024-05-30 WO disclosed
CN-117843543-A Preparation method of alpha, alpha-difluorobutyrolactam 南京工业大学 2024-04-09 CN disclosed
US-20240101562-A1 NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESISTANT CANCER, COMPRISING SAME HOLOSMEDIC (KR) 2024-03-28 US disclosed
WO-2024048778-A1 ARYLTETRAHYDROPYRIDINE COMPOUND AND PEST CONTROL AGENT 日産化学株式会社 2024-03-07 WO disclosed
US-11866515-B2 Hemiasterlin derivatives for conjugation and therapy SUTRO BIOPHARMA, INC. (US) 2024-01-09 US disclosed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
EP-3612180-B1 SUBSTITUTED 2-ACYLAMINO-CYCLOALKYLTHIOPHENE-3-CARBOXYLIC ACID ARYLAMIDES AS INHIBITORS OF CALCIUM-ACTIVATED CHLORIDE CHANNEL TMEM16A UNIV CALIFORNIA (US) 2023-10-11 EP disclosed
WO-2023190286-A1 PEST CONTROLLING AGENT 日本化薬株式会社 2023-10-05 WO disclosed
WO-2004046331-A2 2’-BRANCHED NUCLEOSIDES AND FLAVIVIRIDAE MUTATION IDENIX (CAYMAN) LIMITED (KY) 2004-06-03 WO disclosed
US-20040077587-A1 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections IDENIX PHARMACEUTICALS, INC. 2004-04-22 US disclosed
WO-2004002999-A2 MODIFIED 2' AND 3' -NUCLEOSIDE PRODUGS FOR TREATING FLAVIRIDAE INFECTIONS IDENIX (CAYMAN) LIMITED (KY) 2004-01-08 WO disclosed
WO-2004003000-A2 1’-, 2'- AND 3'- MODIFIED NUCLEOSIDE DERIVATIVES FOR TREATING FLAVIVIRIDAE INFECTIONS IDENIX (CAYMAN) LIMITED (KY) 2004-01-08 WO disclosed
CN-1392133-A Process for preparing bromodifluoacetic acid compounds ATOFINA (FR) 2003-01-22 CN disclosed
EP-1270540-A1 Process for the production of bromo difluoro acetyl compounds Atofina (FR) 2003-01-02 EP disclosed
EP-0194862-B1 PROCESS FOR THE PREPARATION OF FLUOROXY HALO COMPOUNDS AUSIMONT S.p.A. (IT) 1991-09-11 EP disclosed
US-4827024-A Process for the preparation of fluoroxy-halo-compounds AUSIMONT S.P.A. (IT) 1989-05-02 US disclosed
EP-0194862-A2 Process for the preparation of fluoroxy halo compounds AUSIMONT S.p.A. (IT) 1986-09-17 EP disclosed