SCHEMBL465808

SCHEMBL465808

CC(c1ccccc1)(c1ccccc1)C(O)CN1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.52
KMT2A Q03164 3/20 0.51
CYP2D6 P10635 3/20 0.48
TSHR P16473 1/20 0.48
HIF1A Q16665 1/20 0.48
MAOB P27338 1/20 0.48
CHRM2 P08172 2/20 0.47
HTR1A P08908 2/20 0.47
CHRM1 P11229 2/20 0.47
OPRM1 P35372 2/20 0.47
KCNH2 Q12809 2/20 0.47
LMNA P02545 1/20 0.47
KDM4E B2RXH2 4/20 0.47
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP2B6 P20813 1/20 0.46
CHRM4 P08173 1/20 0.45
CHRM5 P08912 1/20 0.45
DRD2 P14416 1/20 0.45
CHRM3 P20309 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678931 0.81 KMT2A (0.48) NPSR1KMT2ACYP2D6TSHRHIF1A
SCHEMBL4881797 0.75 MEN1 (0.58) NPSR1KMT2ACYP2D6TSHRCHRM2
SCHEMBL4890266 0.75 MEN1 (0.58) NPSR1KMT2ACYP2D6TSHRCHRM2
SCHEMBL7721796 0.74 NPSR1 (0.44) NPSR1KMT2ACYP2D6TSHRHIF1A
SCHEMBL14003867 0.74 GAA (0.51) NPSR1KMT2ACYP2D6TSHRCHRM2
SCHEMBL4889873 0.73 MEN1 (0.56) NPSR1KMT2ACYP2D6TSHRCHRM2
SCHEMBL16576732 0.73 KMT2A (0.56) KMT2ACYP2D6TSHRMAOBKCNH2
SCHEMBL8268344 0.72 CYP2B6 (0.47) NPSR1KMT2ACYP2D6CHRM2HTR1A
SCHEMBL14003857 0.72 GAA (0.56) NPSR1KMT2ATSHRCHRM2CHRM1
SCHEMBL14354524 0.71 CHRM2 (0.56) NPSR1KMT2ACYP2D6CHRM2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110268692-A1 Synergistic rodenticidal compositions BAYER CROPSCIENCE AG (DE) 2011-11-03 US disclosed
CN-102176819-A Synergistic rodenticidal agent BAYER CROPSCIENCE AG 2011-09-07 CN disclosed
EP-2343972-A1 SYNERGISTIC RODENTICIDAL AGENT Bayer CropScience AG (DE) 2011-07-20 EP disclosed
CN-101911931-A The bait system that kills mouse BAYER CROPSCIENCE AG 2010-12-15 CN disclosed
US-20100287815-A1 METHOD FOR CONTROLLING HARMFUL RODENTS IN AGRICULTURAL ENTERPRISES BAYER CROPSCIENCE AG (DE) 2010-11-18 US disclosed
WO-2010043322-A1 SYNERGISTIC RODENTICIDAL AGENT BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-04-22 WO disclosed
CN-100521944-C Combination of biological and chemical agents to combat rodents BAYER AG (DE) 2009-08-05 CN disclosed
EP-1389039-B1 METHOD FOR CONTROLLING HARMFUL RODENTS IN AGRICULTURAL ENTERPRISES BAYER CROPSCIENCE AG (DE) 2008-11-12 EP disclosed
US-7008632-B2 Combination of biological and chemical agents to combat rodents BAYER AKTIENGESELLSCHAFT (DE) 2006-03-07 US disclosed
CN-1665389-A Deratization bait system BAYER CROPSCIENCE AG (DE) 2005-09-07 CN disclosed
EP-1251740-A2 COMBINATION OF BIOLOGICAL AND CHEMICAL AGENTS TO COMBAT RODENTS Bayer Aktiengesellschaft (DE) 2002-10-30 EP disclosed
WO-2001052654-A2 COMBINATION OF BIOLOGICAL AND CHEMICAL AGENTS TO COMBAT RODENTS BAYER AKTIENGESELLSCHAFT (DE) 2001-07-26 WO disclosed
US-6036970-A POISONS FOR ANIMALS SUCH AS RODENTS BAYER AKTIENGESELLSCHAFT (DE) 2000-03-14 US disclosed
EP-0719498-B1 Rodenticidal foams BAYER AG (DE) 1999-05-26 EP disclosed
EP-0789998-B1 Rodenticidal foams BAYER AG (DE) 1998-05-06 EP disclosed
EP-0789998-A1 Rodenticidal foams BAYER AG (DE) 1997-08-20 EP disclosed
EP-0784427-A1 RODENTICIDAL BAIT SYSTEMS BAYER AG (DE) 1997-07-23 EP disclosed
EP-0719498-A1 Rodenticidal foams BAYER AG (DE) 1996-07-03 EP disclosed
WO-1996009758-A1 RODENTICIDAL BAIT SYSTEMS BAYER AKTIENGESELLSCHAFT (DE) 1996-04-04 WO disclosed
US-4011332-A RODENTICIDE BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1977-03-08 US disclosed