Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.67 |
| ▸ | CHUK | O15111 | 4/20 | 0.62 |
| ▸ | EPHA3 | P29320 | 3/20 | 0.62 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282636 | 0.91 | IKBKB (0.68) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4917527 | 0.90 | IKBKB (0.63) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4718612 | 0.89 | IKBKB (0.52) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4922537 | 0.89 | IKBKB (0.64) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4912375 | 0.89 | IKBKB (0.64) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4920056 | 0.89 | IKBKB (0.64) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4657009 | 0.89 | IKBKB (0.72) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4657586 | 0.89 | IKBKB (0.72) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4657585 | 0.89 | IKBKB (0.72) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL6285001 | 0.88 | IKBKB (0.68) | IKBKBCHUKEPHA3NTRK1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536646-A | Nematicidal active compound and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | claimed |
| EP-2008654-A1 | 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amides | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2008-12-31 | — | — | EP | claimed |
| EP-1513516-B1 | SUBSTITUTED 3-AMINO-THIENO(2,3-b) PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | BOEHRINGER INGELHEIM PHARMA (US) | 2008-12-03 | — | — | EP | claimed |
| US-20050288285-A1 | Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | US | claimed |
| US-6974870-B2 | Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHAMACEUTICALS, INC. (US) | 2005-12-13 | — | — | US | claimed |
| EP-1513516-A1 | SUBSTITUTED 3-AMINO-THIENO(2,3-b) PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS ANDPROCESSES FOR PREPARING AND THEIR USES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-03-16 | — | — | EP | claimed |
| US-20040180922-A1 | Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-09-16 | — | — | US | claimed |
| US-20040053957-A1 | Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-03-18 | — | — | US | claimed |
| WO-2003103661-A1 | SUBSTITUTED 3-AMINO-THIENO[2,3-b]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | claimed |
| US-5389602-A | PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1995-02-14 | — | — | US | claimed |
| EP-0345635-B1 | Herbicidal tetrahydropyran-2,4-diones | BASF AG (DE) | 1994-10-05 | — | — | EP | claimed |
| US-5166399-A | SUBSTITUTED OXIME ETHERS AND FUNGICIDES WHICH CONTAIN THESE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | claimed |
| EP-0121171-B1 | FUNGICIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1989-05-10 | — | — | EP | claimed |
| EP-0105166-B1 | SUBSTITUTED TERT. BUTANOL DERIVATIVES, METHOD FOR THEIR PREPARATION AND ANTIMYCOTIC AGENTS CONTAINING THEM | BAYER AG (DE) | 1987-04-22 | — | — | EP | claimed |
| CN-115536646-A | Nematicidal active compound and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | disclosed |
| EP-2008654-A1 | 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amides | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2008-12-31 | — | — | EP | disclosed |
| EP-1513516-B1 | SUBSTITUTED 3-AMINO-THIENO(2,3-b) PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | BOEHRINGER INGELHEIM PHARMA (US) | 2008-12-03 | — | — | EP | disclosed |
| US-4740516-A | Substituted t-butanol fungicidal agents | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |
| US-4621095-A | BIS-AZOLYL-SUBSTITUTED TERT-BUTANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-04 | — | — | US | disclosed |
| US-4618619-A | Substituted t-butanol fungicidal agents | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053957-A1 | Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | NFKBIA, IKBKB, CHUK | IKBKB 2/4885CHUK 3/4885EPHA3 4274/4885 |
| US-20050288285-A1 | Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | NFKBIA, CHUK, IKBKB | IKBKB 3/4885CHUK 2/4885EPHA3 4318/4885 |
| US-20040180922-A1 | Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | NFKBIA, IKBKB, CHUK | IKBKB 2/4885CHUK 3/4885EPHA3 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.