Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 18/20 | 0.43 |
| ▸ | CHUK | O15111 | 2/20 | 0.43 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656552 | 0.91 | IKBKB (0.45) | IKBKBCHUKEPHA3NTRK1GAK | |
| SCHEMBL4657206 | 0.91 | IKBKB (0.44) | IKBKBCHUKEPHA3NTRK1GAK | |
| SCHEMBL4657803 | 0.87 | IKBKB (0.57) | IKBKBCHUKEPHA3NTRK1GAK | |
| SCHEMBL4657798 | 0.87 | IKBKB (0.57) | IKBKBCHUKEPHA3NTRK1GAK | |
| SCHEMBL4658251 | 0.79 | IKBKB (0.56) | IKBKBCHUKEPHA3NTRK1GAK | |
| SCHEMBL4658255 | 0.79 | IKBKB (0.56) | IKBKBCHUKEPHA3NTRK1GAK | |
| SCHEMBL4657018 | 0.78 | IKBKB (0.60) | IKBKBCHUKEPHA3NTRK1GAK | |
| SCHEMBL4657014 | 0.78 | IKBKB (0.60) | IKBKBCHUKEPHA3NTRK1GAK | |
| SCHEMBL4657865 | 0.77 | IKBKB (0.59) | IKBKBCHUKEPHA3NTRK1GAK | |
| SCHEMBL4657859 | 0.77 | IKBKB (0.59) | IKBKBCHUKEPHA3NTRK1GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513516-B1 | SUBSTITUTED 3-AMINO-THIENO(2,3-b) PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | BOEHRINGER INGELHEIM PHARMA (US) | 2008-12-03 | — | — | EP | claimed |