Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548137 | 0.89 | DPP4 (0.66) | DPP4CHRM1 | |
| SCHEMBL3548133 | 0.89 | DPP4 (0.66) | DPP4CHRM1 | |
| SCHEMBL638643 | 0.83 | DPP4 (0.74) | DPP4CHRM1 | |
| SCHEMBL638399 | 0.83 | DPP4 (0.73) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL638642 | 0.83 | DPP4 (0.74) | DPP4CHRM1 | |
| SCHEMBL3551601 | 0.79 | DPP4 (0.68) | DPP4CHRM1CHRM3 | |
| SCHEMBL3551598 | 0.79 | DPP4 (0.68) | DPP4CHRM1CHRM3 | |
| SCHEMBL3551368 | 0.77 | DPP4 (0.70) | DPP4CHRM1 | |
| SCHEMBL5842625 | 0.73 | DPP4 (0.71) | DPP4CHRM1 | |
| SCHEMBL5842641 | 0.73 | DPP4 (0.71) | DPP4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720875-B1 | 8- [3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2008-12-10 | — | — | EP | disclosed |