Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.55 |
| ▸ | CHUK | O15111 | 4/20 | 0.51 |
| ▸ | EPHA3 | P29320 | 3/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4658259 | 1.00 | IKBKB (0.55) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4659339 | 1.00 | IKBKB (0.55) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4657958 | 0.95 | IKBKB (0.56) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4659303 | 0.93 | IKBKB (0.55) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4718931 | 0.93 | IKBKB (0.53) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4656985 | 0.93 | IKBKB (0.53) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4656577 | 0.93 | IKBKB (0.54) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4658044 | 0.93 | IKBKB (0.56) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4657940 | 0.92 | IKBKB (0.54) | IKBKBCHUKEPHA3NTRK1PDGFRA | |
| SCHEMBL4656431 | 0.92 | IKBKB (0.55) | IKBKBCHUKEPHA3NTRK1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513516-B1 | SUBSTITUTED 3-AMINO-THIENO(2,3-b) PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | BOEHRINGER INGELHEIM PHARMA (US) | 2008-12-03 | — | — | EP | claimed |