Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499080 | 0.89 | ACE (0.50) | RENACE | |
| SCHEMBL1734898 | 0.88 | DPP4 (0.40) | RENACE | |
| SCHEMBL12253005 | 0.84 | DPP4 (0.40) | — | |
| SCHEMBL4956515 | 0.82 | POLB (0.41) | — | |
| SCHEMBL4956518 | 0.82 | POLB (0.41) | — | |
| SCHEMBL6135700 | 0.81 | DPP7 (0.39) | — | |
| SCHEMBL6135698 | 0.81 | DPP7 (0.39) | — | |
| SCHEMBL4600121 | 0.79 | — | — | |
| SCHEMBL2210117 | 0.79 | NPSR1 (0.36) | — | |
| SCHEMBL4600126 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542968-B1 | PROCESS FOR PREPARING INTERMEDIATES | NOVARTIS AG (CH) | 2008-12-17 | — | — | EP | disclosed |
| US-7323448-B2 | Antibacterial agents | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2008-01-29 | — | — | US | disclosed |
| US-7323448-B2 | Antibacterial agents | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2008-01-29 | — | — | US | disclosed |