SCHEMBL4660348

SCHEMBL4660348

COC(=O)OC(=O)[C@@H](N)CS

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.44
SLC7A11 Q9UPY5 1/20 0.44
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33
NFKB1 P19838 1/20 0.33
PTGS2 P35354 1/20 0.33
THPO P40225 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ENPEP Q07075 6/20 0.32
SOAT1 P35610 1/20 0.31
SLC1A1 P43005 1/20 0.31
ANPEP P15144 2/20 0.30
MMP2 P08253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29191449 0.86 PTGS1 (0.48) PTGS1SLC7A11ENPEPANPEP
Mecysteine SCHEMBL1681698 0.84
Mecysteine SCHEMBL94255 0.84
Mecysteine SCHEMBL21034 0.84
SCHEMBL1964879 0.84 PTGS1 (0.55) PTGS1SLC7A11ENPEPANPEPMMP2
SCHEMBL20657045 0.84 PTGS1 (0.55) PTGS1SLC7A11ENPEPANPEPMMP2
Mecysteine SCHEMBL21033 0.82
Mecysteine SCHEMBL5685920 0.82
Mecysteine SCHEMBL5685917 0.82
Mecysteine SCHEMBL1681697 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3461475-A1 PHARMACEUTICAL COMPOSITION CONTAINING SYMPATHOMIMETIC AMINE SALT AND CO-DISTILLABLE ADDITIVE Wyeth LLC (US) 2019-04-03 EP claimed
EP-2004147-B1 PHARMACEUTICAL COMPOSITION CONTAINING SYMPATHOMIMETIC AMINE SALT AND CO-DISTILLABLE ADDITIVE WYETH LLC (US) 2019-01-02 EP claimed
US-9238073-B2 Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive WYETH LLC (US) 2016-01-19 US claimed
CN-101420936-A Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive WYETH CORP (US) 2009-04-29 CN claimed
EP-2004147-A2 PHARMACEUTICAL COMPOSITION CONTAINING SYMPATHOMIMETIC AMINE SALT AND CO-DISTILLABLE ADDITIVE Wyeth a Corporation of the State of Delaware (US) 2008-12-24 EP claimed
WO-2007120725-A2 PHARMACEUTICAL COMPOSITION CONTAINING SYMPATHOMIMETIC AMINE SALT AND CO-DISTILLABLE ADDITIVE WYETH (US) 2007-10-25 WO claimed
US-20070243140-A1 Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive HALEON US HOLDINGS LLC 2007-10-18 US claimed
US-10307485-B2 Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive WYETH LLC (US) 2019-06-04 US disclosed
EP-3461475-A1 PHARMACEUTICAL COMPOSITION CONTAINING SYMPATHOMIMETIC AMINE SALT AND CO-DISTILLABLE ADDITIVE Wyeth LLC (US) 2019-04-03 EP disclosed
EP-2004147-B1 PHARMACEUTICAL COMPOSITION CONTAINING SYMPATHOMIMETIC AMINE SALT AND CO-DISTILLABLE ADDITIVE WYETH LLC (US) 2019-01-02 EP disclosed
US-20170258916-A1 Pharmaceutical Composition Containing Sympathomimetic Amine Salt and Co-distillable Additive WYETH LLC (US) 2017-09-14 US disclosed
US-9238073-B2 Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive WYETH LLC (US) 2016-01-19 US disclosed
US-20150272909-A1 Pharmaceutical Composition Containing Sympathomimetic Amine Salt and Co-distillable Additive WYETH LLC (US) 2015-10-01 US disclosed
EP-2004147-A2 PHARMACEUTICAL COMPOSITION CONTAINING SYMPATHOMIMETIC AMINE SALT AND CO-DISTILLABLE ADDITIVE Wyeth a Corporation of the State of Delaware (US) 2008-12-24 EP disclosed
WO-2007120725-A2 PHARMACEUTICAL COMPOSITION CONTAINING SYMPATHOMIMETIC AMINE SALT AND CO-DISTILLABLE ADDITIVE WYETH (US) 2007-10-25 WO disclosed
US-20070243140-A1 Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive HALEON US HOLDINGS LLC 2007-10-18 US disclosed