Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659036 | 0.91 | CHRM2 (0.51) | CHRM2CHRM1KMT2AKEAP1NFE2L2 | |
| SCHEMBL4660409 | 0.91 | CHRM2 (0.51) | CHRM2CHRM1KMT2AKEAP1NFE2L2 | |
| SCHEMBL4660350 | 0.91 | CHRM2 (0.46) | CHRM2CHRM1KMT2AESR1ESR2 | |
| SCHEMBL4659037 | 0.90 | CHRM2 (0.46) | CHRM2CHRM1KMT2ATP53GAA | |
| SCHEMBL4661597 | 0.88 | CHRM2 (0.46) | CHRM2CHRM1KMT2AGAAACHE | |
| SCHEMBL4659055 | 0.86 | CHRM2 (0.43) | CHRM2CHRM1KMT2AGAATHRB | |
| SCHEMBL4660336 | 0.85 | CHRM2 (0.47) | CHRM2CHRM1KMT2AESR1ESR2 | |
| SCHEMBL1158251 | 0.84 | CHRM2 (0.62) | CHRM2CHRM1KMT2ATP53ACHE | |
| SCHEMBL4659057 | 0.84 | CHRM2 (0.62) | CHRM2CHRM1KMT2ATP53ACHE | |
| Hydrochloric Acid SCHEMBL16166361 | 0.84 | CHRM2 (0.61) | CHRM2CHRM1KMT2AACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254890-A1 | Derivatives of 3,3-diphenylpropylamines | SCHWARZ PHARMA AG (DE) | 2002-11-06 | — | — | EP | claimed |
| EP-2004592-A1 | SYNTHESIS OF PHENOLIC ESTERS OF HYDROXYMETHYL PHENOLS | Schwarz Pharma Ltd. (IE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007140986-A1 | SYNTHESIS OF PHENOLIC ESTERS OF HYDROXYMETHYL PHENOLS | SCHWARZ PHARMA LTD (IE) | 2007-12-13 | — | — | WO | disclosed |