Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617673 | 0.93 | ABCB1 (0.51) | ABCB1CYP3A4 | |
| SCHEMBL3769756 | 0.93 | ABCB1 (0.51) | ABCB1CYP3A4 | |
| SCHEMBL4659137 | 0.85 | ABCB1 (0.55) | ABCB1CYP3A4 | |
| SCHEMBL13003219 | 0.85 | ABCB1 (0.55) | ABCB1CYP3A4 | |
| SCHEMBL13003227 | 0.84 | ABCB1 (0.49) | ABCB1CYP3A4 | |
| SCHEMBL3778940 | 0.84 | ABCB1 (0.49) | ABCB1CYP3A4 | |
| SCHEMBL7476971 | 0.83 | ABCB1 (0.50) | ABCB1CYP3A4 | |
| SCHEMBL14937459 | 0.83 | ABCB1 (0.44) | ABCB1CYP3A4 | |
| SCHEMBL14937148 | 0.83 | NPC1 (0.32) | ABCB1CYP3A4 | |
| SCHEMBL13003221 | 0.81 | ABCB1 (0.48) | ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603860-A4 | DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS VIA AN ECDYSONE RECEPTOR COMPLEX | INTREXON CORP (US) | 2008-05-14 | — | — | EP | disclosed |
| EP-1603860-A2 | DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS VIA AN ECDYSONE RECEPTOR COMPLEX | RheoGene Holdings Inc. (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004072254-A2 | DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS VIA AN ECDYSONE RECEPTOR COMPLEX | RHEOGENE HOLDINGS, INC (US) | 2004-08-26 | — | — | WO | disclosed |