Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 11/20 | 0.49 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.43 |
| ▸ | SLC34A3 | Q8N130 | 1/20 | 0.43 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.43 |
| ▸ | ADCYAP1R1 | P41586 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45091 | 0.93 | SLC34A2 (0.49) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL40226 | 0.93 | SLC34A2 (0.49) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL15421175 | 0.93 | SLC34A2 (0.48) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL40444 | 0.93 | SLC34A2 (0.48) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL15444463 | 0.93 | SLC34A2 (0.49) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL10274308 | 0.93 | SLC34A2 (0.49) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL40710 | 0.93 | SLC34A2 (0.49) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL47010 | 0.91 | SLC34A2 (0.49) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL265714 | 0.91 | SLC34A2 (0.52) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 | |
| SCHEMBL274037 | 0.91 | SLC34A2 (0.52) | SLC34A2SLC34A1SLC34A3SLC20A1ADCYAP1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |