Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2638613 | 0.89 | S1PR1 (0.71) | S1PR1S1PR3 | |
| SCHEMBL2638745 | 0.86 | S1PR1 (0.56) | S1PR1S1PR3 | |
| SCHEMBL1567378 | 0.84 | S1PR1 (0.80) | S1PR1S1PR3 | |
| SCHEMBL1567376 | 0.84 | S1PR1 (0.80) | S1PR1S1PR3 | |
| SCHEMBL4664504 | 0.77 | S1PR1 (0.55) | S1PR1S1PR3 | |
| SCHEMBL2639905 | 0.76 | S1PR1 (0.67) | S1PR1S1PR3 | |
| SCHEMBL4664536 | 0.76 | S1PR1 (0.71) | S1PR1S1PR3 | |
| SCHEMBL2433683 | 0.76 | S1PR1 (0.70) | S1PR1S1PR3 | |
| SCHEMBL2639815 | 0.75 | S1PR1 (0.73) | S1PR1S1PR3 | |
| SCHEMBL4664648 | 0.75 | S1PR1 (0.73) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633336-A4 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-10-29 | — | — | EP | disclosed |
| EP-1633336-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004103306-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-12-02 | — | — | WO | disclosed |