SCHEMBL4663595

SCHEMBL4663595

[CH2]C[CH]C=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL973906 0.75
SCHEMBL832962 0.67
SCHEMBL21121227 0.67
SCHEMBL247521 0.67
SCHEMBL4557216 0.67
SCHEMBL5675181 0.67
SCHEMBL1328 0.64
SCHEMBL975733 0.64
SCHEMBL974374 0.61
SCHEMBL21806850 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105037278-B Sirt5 regulator and its screening technique 康奈尔大学 2019-05-03 CN disclosed
CN-105037278-A Modulators for Sirt5 and assays for screening same UNIV CORNELL 2015-11-11 CN disclosed
CN-103097545-B Sirt5 modulators and screening methods thereof UNIV CORNELL 2015-07-22 CN disclosed
CN-103097545-A Sirt5 modulators and screening methods thereof UNIV CORNELL 2013-05-08 CN disclosed
US-20080193700-A1 Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2008-08-14 US disclosed
EP-1743333-A1 METAL CHELATES AND THEIR USE IN OPTICAL RECORDING MEDIA HAVING HIGH STORAGE CAPACITY CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-01-17 EP disclosed
EP-1710793-A1 Metal chelate compounds and high capacity optical recording medium using the compounds Ciba SC Holding AG (CH) 2006-10-11 EP disclosed
WO-2005106868-A1 METAL CHELATES AND THEIR USE IN OPTICAL RECORDING MEDIA HAVING HIGH STORAGE CAPACITY CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-11-10 WO disclosed
EP-0609058-B1 Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses SANKYO CO (JP) 1998-12-09 EP disclosed
US-5491167-A INHIBITORS OF CHOLESTEROL BIOSYNTHESIS SANKYO COMPANY, LIMITED (JP) 1996-02-13 US disclosed
EP-0609058-A2 Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses SANKYO COMPANY LIMITED (JP) 1994-08-03 EP disclosed