Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.34 |
| ▸ | FDPS | P14324 | 9/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662878 | 1.00 | TSHR (0.36) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL4664662 | 1.00 | TSHR (0.36) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL4664587 | 1.00 | TSHR (0.36) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL4662877 | 0.98 | SPHK2 (0.33) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL13864573 | 0.95 | TSHR (0.36) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL13517609 | 0.91 | TSHR (0.40) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL13517699 | 0.91 | TSHR (0.40) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL967960 | 0.91 | TSHR (0.40) | TSHRTHRBSPHK2SPHK1GGPS1 | |
| SCHEMBL1276923 | 0.91 | SPHK2 (0.31) | SPHK2SPHK1 | |
| SCHEMBL13517112 | 0.88 | TSHR (0.38) | TSHRTHRBSPHK2SPHK1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064836-A1 | Process for the preparation of ethylene copolymers | BASELL POLIOLEFINE ITALIA S.R.I. (IT) | 2008-03-13 | — | — | US | claimed |
| US-20050107539-A1 | Process for the preparation of ethylene copolymers | BASELL POLIOLEFINE ITALIA S. P. A. (IT) | 2005-05-19 | — | — | US | claimed |
| EP-1511778-A2 | PROCESS FOR THE PREPARATION OF ETHYLENE COPOLYMERS | Basell Poliolefine Italia S.P.A. (IT) | 2005-03-09 | — | — | EP | claimed |
| WO-2003106514-A2 | PROCESS FOR THE PREPARATION OF ETHYLENE COPOLYMERS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-12-24 | — | — | WO | claimed |
| US-8394734-B2 | Solid catalyst for propylene polymerization and a method for preparation of polypropylene using the same | SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) | 2013-03-12 | — | — | US | disclosed |
| US-20120277389-A1 | SOLID CATALYST FOR PROPYLENE POLYMERIZATION AND A METHOD FOR PREPARATION OF POLYPROPYLENE USING THE SAME | SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) | 2012-11-01 | — | — | US | disclosed |
| US-20080182941-A1 | Polyolefin compositions | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2008-07-31 | — | — | US | disclosed |
| US-7371806-B2 | Process for the preparation of ethylene copolymers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2008-05-13 | — | — | US | disclosed |
| US-20080064836-A1 | Process for the preparation of ethylene copolymers | BASELL POLIOLEFINE ITALIA S.R.I. (IT) | 2008-03-13 | — | — | US | disclosed |
| US-20050107539-A1 | Process for the preparation of ethylene copolymers | BASELL POLIOLEFINE ITALIA S. P. A. (IT) | 2005-05-19 | — | — | US | disclosed |
| EP-1511778-A2 | PROCESS FOR THE PREPARATION OF ETHYLENE COPOLYMERS | Basell Poliolefine Italia S.P.A. (IT) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003106514-A2 | PROCESS FOR THE PREPARATION OF ETHYLENE COPOLYMERS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-12-24 | — | — | WO | disclosed |