⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1792942 | 1.00 | — | — | |
| SCHEMBL9191419 | 1.00 | — | — | |
| SCHEMBL12057002 | 0.92 | EPHX1 (0.32) | — | |
| SCHEMBL2929180 | 0.80 | — | — | |
| SCHEMBL14342998 | 0.80 | — | — | |
| SCHEMBL421978 | 0.75 | — | — | |
| SCHEMBL511710 | 0.73 | — | — | |
| SCHEMBL31268428 | 0.72 | — | — | |
| SCHEMBL8036525 | 0.72 | — | — | |
| SCHEMBL2357946 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930021-A2 | Novel amide derivatives as growth hormone secretagogues | Kaken Pharmaceutical Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
| EP-1158996-A4 | NOVEL AMIDE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUES | KAKEN PHARMA CO LTD (JP) | 2005-01-12 | — | — | EP | disclosed |
| EP-1158996-A1 | NOVEL AMIDE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUES | Kaken Pharmaceutical Co., Ltd. (JP) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000048623-A1 | NOVEL AMIDE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |
| US-5455273-A | Antiacholesterol agents | KARL THOMAE GMBH (DE) | 1995-10-03 | — | — | US | disclosed |