Formic Acid

Formic Acid

SCHEMBL4665644

Cc1ccc(S(=O)(=O)Nc2ccc(Nc3cc(-c4ccc(OCCC5CCN(C)CC5)cc4)ncn3)cc2)cc1.O=CO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 4/20 0.44
BCR P11274 4/20 0.44
MAPT P10636 4/20 0.42
PDE4D Q08499 1/20 0.42
GSK3B P49841 1/20 0.40
GAA P10253 1/20 0.40
TP53 P04637 1/20 0.38
NPY5R Q15761 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL4666189 0.94 ABL1 (0.46) ABL1BCRMAPTGSK3B
Formic Acid SCHEMBL4665852 0.92 ABL1 (0.43) ABL1BCRMAPTPDE4DGSK3B
Formic Acid SCHEMBL4665817 0.89 ABL1 (0.43) ABL1BCRMAPTGAA
Formic Acid SCHEMBL4667407 0.87 ABL1 (0.44) ABL1BCR
Formic Acid SCHEMBL4665613 0.86 ABL1 (0.47) ABL1BCRGSK3B
Formic Acid SCHEMBL4663881 0.86 HRH3 (0.48) ABL1BCRMAPT
Formic Acid SCHEMBL4667491 0.86 ABL1 (0.44) ABL1BCRGSK3B
Formic Acid SCHEMBL4666071 0.86 ABL1 (0.48) ABL1BCRGSK3BTP53NPY5R
Formic Acid SCHEMBL4665776 0.85 ABL1 (0.43) ABL1BCRTP53
Formic Acid SCHEMBL4665720 0.85 HRH3 (0.53) ABL1BCRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080242681-A1 N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors ALTANA PHARMA AG (DE) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242681-A1 N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors MAP3K19, MAP3K6, MAP3K20 ABL1 24/4885BCR 402/4885MAPT 4521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.