Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 8/20 | 0.49 |
| ▸ | BCR | P11274 | 7/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664333 | 0.91 | TP53 (0.49) | CYP1A2CYP2D6CYP2C19CLK4CYP3A4 | |
| SCHEMBL4663960 | 0.90 | ABL1 (0.57) | ABL1BCRBACE1MEN1NPC1 | |
| SCHEMBL4664312 | 0.88 | SLC22A12 (0.52) | CYP1A2CYP2D6CYP2C19CLK4CYP3A4 | |
| SCHEMBL4665707 | 0.87 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP2C19CLK4CYP3A4 | |
| SCHEMBL17022942 | 0.84 | CYP1A2 (0.69) | CYP1A2CYP2D6CYP2C19CLK4CYP3A4 | |
| SCHEMBL4663875 | 0.83 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP2C19CLK4CYP3A4 | |
| SCHEMBL4665836 | 0.83 | AXL (0.48) | CYP1A2CYP2D6CYP2C19CLK4CYP3A4 | |
| SCHEMBL4109389 | 0.82 | EGFR (0.54) | CYP1A2CYP2D6CYP2C19CLK4CYP3A4 | |
| SCHEMBL4667528 | 0.81 | ABL1 (0.57) | ABL1BCRBACE1MEN1NPC1 | |
| SCHEMBL4665847 | 0.81 | ABL1 (0.51) | CYP1A2CYP2D6CYP2C19CLK4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | CYP1A2 1215/4885CYP2D6 646/4885CYP2C19 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.