Acrylamide

Acrylamide

SCHEMBL4665950

C=CC(N)=O.CC(C(=O)O)S(=O)(=O)O

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
FGFR4 P22455 1/20 0.46
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31
GABRA1 P14867 2/20 0.31
GABRB1 P18505 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRA3 P34903 2/20 0.31
GABRA2 P47869 2/20 0.31
GABRB2 P47870 2/20 0.31
GABRA4 P48169 2/20 0.31
GABRE P78334 2/20 0.31
GABRA6 Q16445 2/20 0.31
GABRG1 Q8N1C3 2/20 0.31
GABRG3 Q99928 2/20 0.31
GABRQ Q9UN88 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL2099063 0.82 TSHR (0.55) TSHRALDH1A1FGFR4LMNA
SCHEMBL792711 0.82
Acrylamide SCHEMBL2771322 0.80 TSHR (0.52) TSHRALDH1A1FGFR4
Acrylamide SCHEMBL29249902 0.80 TSHR (0.52) TSHRALDH1A1FGFR4
Acrylamide SCHEMBL2196034 0.80 TSHR (0.58) TSHRALDH1A1FGFR4LMNA
SCHEMBL28011704 0.79 TP53 (0.40) ALDH1A1SLC7A5
SCHEMBL28011721 0.79 TP53 (0.40) ALDH1A1SLC7A5
SCHEMBL8373173 0.79 TP53 (0.40) ALDH1A1SLC7A5
SCHEMBL29289425 0.79 TP53 (0.40) ALDH1A1SLC7A5
Acrylamide SCHEMBL27553594 0.75 TSHR (0.46) TSHRALDH1A1FGFR4SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1435380-B1 Polymer additive for ink-jet inks to improve durability HEWLETT PACKARD DEVELOPMENT CO (US) 2008-04-16 EP claimed
EP-0700987-B1 Method of inhibiting corrosion in aqueous systems ROHM & HAAS (US) 2001-03-28 EP disclosed
EP-0705794-B1 Method of inhibiting sulfate scale in aqueous systems ROHM & HAAS (US) 2000-01-12 EP disclosed
US-5658464-A ADDING HOMO OR COPOLYMER OF POLYAMINO ACIDS WITH INORGANIC PHOSPHATE IN AQUOUS SOLUTION CONTAINING METAL SULFATE SCALES ROHM AND HAAS COMPANY (US) 1997-08-19 US disclosed
US-5531934-A POLYASPARTIC ACID AND POLYGLUTAMIC ACID WITH PYROPHOSPHATE FOR CORROSION RESISTANCE OF FERROUS METALS ROHM & HAAS COMPANY (US) 1996-07-02 US disclosed
EP-0705794-A2 Method of inhibiting sulfate scale in aqueous systems ROHM AND HAAS COMPANY (US) 1996-04-10 EP disclosed
EP-0700987-A2 Method of inhibiting corrosion in aqueous systems ROHM AND HAAS COMPANY (US) 1996-03-13 EP disclosed