Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636374 | 0.88 | GRM5 (0.46) | GRM5 | |
| SCHEMBL4321267 | 0.87 | GRM5 (0.39) | GRM5 | |
| SCHEMBL4334637 | 0.83 | GRM5 (0.51) | GRM5 | |
| SCHEMBL4337089 | 0.82 | GRM5 (0.41) | GRM5 | |
| SCHEMBL4330073 | 0.80 | GRM5 (0.46) | GRM5CYP11B2 | |
| SCHEMBL4335199 | 0.78 | GRM5 (0.59) | GRM5 | |
| SCHEMBL4636391 | 0.78 | GRM5 (0.54) | GRM5 | |
| SCHEMBL4333942 | 0.76 | GRM5 (0.67) | GRM5 | |
| SCHEMBL4335240 | 0.75 | GRM5 (0.55) | GRM5 | |
| SCHEMBL4335449 | 0.75 | GRM5 (0.59) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931635-A1 | TETRAHYDROQUINOLINONES AND THEIR USE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Merz Pharma GmbH & Co.KGaA (DE) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007023290-A1 | TETRAHYDROQUINOLINONES AND THEIR USE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-03-01 | — | — | WO | disclosed |