SCHEMBL466680

SCHEMBL466680

C/C=C/CCCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 2/20 0.32
FAAH O00519 2/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SOAT1 P35610 1/20 0.30
LPAR2 Q9HBW0 3/20 0.30
LPAR3 Q9UBY5 3/20 0.30
LPAR1 Q92633 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466690 1.00 TOP1 (0.32) TOP1FAAHALDH1A1CYP3A4ALOX15
SCHEMBL466620 1.00 TOP1 (0.32) TOP1FAAHALDH1A1CYP3A4ALOX15
SCHEMBL466681 1.00 TOP1 (0.32) TOP1FAAHALDH1A1CYP3A4ALOX15
SCHEMBL31572359 1.00 TOP1 (0.32) TOP1FAAHALDH1A1CYP3A4ALOX15
SCHEMBL466621 1.00 TOP1 (0.32) TOP1FAAHALDH1A1CYP3A4ALOX15
SCHEMBL466689 1.00 TOP1 (0.32) TOP1FAAHALDH1A1CYP3A4ALOX15
SCHEMBL467218 0.98
SCHEMBL467219 0.98
SCHEMBL466811 0.92
SCHEMBL466810 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877857-B2 Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-11-04 US disclosed
EP-2404944-B1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE SUMITOMO RUBBER IND (JP) 2014-05-14 EP disclosed
CN-102365306-B Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER IND 2014-04-02 CN disclosed
US-20120095153-A1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-04-19 US disclosed
CN-102365306-A Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER IND 2012-02-29 CN disclosed
EP-2404944-A1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE Sumitomo Rubber Industries, Ltd. (JP) 2012-01-11 EP disclosed