Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 12/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600989 | 0.91 | DHODH (0.49) | DHODH | |
| SCHEMBL4665857 | 0.81 | DHODH (0.42) | DHODHMALT1KDM4EPOLB | |
| SCHEMBL14600461 | 0.79 | DHODH (0.51) | DHODH | |
| SCHEMBL14600455 | 0.78 | DHODH (0.47) | DHODH | |
| SCHEMBL14600459 | 0.77 | DHODH (0.49) | DHODH | |
| SCHEMBL4666242 | 0.76 | CRACR2A (0.38) | MALT1KDM4EPOLB | |
| SCHEMBL14600460 | 0.75 | DHODH (0.51) | DHODH | |
| SCHEMBL14600254 | 0.73 | ADORA1 (0.51) | DHODH | |
| SCHEMBL4665671 | 0.73 | P2RY1 (0.37) | DHODHKDM4EPOLB | |
| SCHEMBL14600261 | 0.73 | DHODH (0.52) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |