Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 6/20 | 0.36 |
| ▸ | ACACA | Q13085 | 6/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668391 | 0.93 | NPY2R (0.43) | MAPTALDH1A1NPY2RTP53LMNA | |
| SCHEMBL4666685 | 0.93 | NPY2R (0.43) | MAPTALDH1A1NPY2RTP53LMNA | |
| SCHEMBL4666686 | 0.93 | NPY2R (0.43) | MAPTALDH1A1NPY2RTP53LMNA | |
| Hydrochloric Acid SCHEMBL4669546 | 0.92 | NPY2R (0.42) | MAPTALDH1A1NPY2RTP53LMNA | |
| Hydrochloric Acid SCHEMBL4667246 | 0.92 | NPY2R (0.42) | MAPTALDH1A1NPY2RTP53LMNA | |
| SCHEMBL4666695 | 0.86 | HRH3 (0.41) | MAPTALDH1A1TP53HRH3ACACB | |
| SCHEMBL4666773 | 0.86 | HRH3 (0.41) | MAPTALDH1A1TP53HRH3ACACB | |
| SCHEMBL4668242 | 0.86 | HRH3 (0.41) | MAPTALDH1A1TP53HRH3ACACB | |
| Hydrochloric Acid SCHEMBL4668308 | 0.86 | HRH3 (0.40) | MAPTALDH1A1TP53HRH3ACACB | |
| Hydrochloric Acid SCHEMBL4666655 | 0.86 | HRH3 (0.40) | MAPTALDH1A1TP53HRH3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802307-B1 | PYRROLIDINE DERIVATIVES AS HISTAMINE RECEPTORS LIGANDS | GLAXO GROUP LTD (GB) | 2008-02-27 | — | — | EP | claimed |