Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.74 |
| ▸ | ESR1 | P03372 | 19/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.57 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | PLD2 | O14939 | 1/20 | 0.55 |
| ▸ | ESRRB | O95718 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667554 | 0.92 | CYP19A1 (0.64) | CYP19A1ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL4667548 | 0.92 | ESR1 (0.66) | CYP19A1ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL4665856 | 0.90 | CYP19A1 (0.60) | CYP19A1ESR1ESR2ESRRBESRRG | |
| SCHEMBL4667511 | 0.87 | ESR1 (0.59) | CYP19A1ESR1ESR2ESRRBESRRG | |
| SCHEMBL4638589 | 0.86 | ESR1 (0.89) | ESR1ESR2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL31167386 | 0.85 | CYP19A1 (1.00) | CYP19A1ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL3813077 | 0.84 | CYP19A1 (0.89) | CYP19A1ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL14531703 | 0.84 | ESR1 (0.65) | CYP19A1ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL4667966 | 0.84 | ESR1 (0.69) | CYP19A1ESR1ESR2 | |
| SCHEMBL4668900 | 0.83 | ESR1 (0.55) | CYP19A1ESR1ESR2ESRRBESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | KATAMREDDY SUBBA REDDY | 2008-10-16 | — | — | US | disclosed |
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | KATAMREDDY SUBBA REDDY | 2008-10-16 | — | — | US | disclosed |
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | KATAMREDDY SUBBA REDDY | 2008-10-16 | — | — | US | disclosed |
| EP-1951216-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062145-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | GPER1, ESR2, ESRRG | CYP19A1 7/4885ESR1 4/4885ESR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.