Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 17/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600707 | 0.91 | ADORA1 (0.43) | DHODHADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL14600461 | 0.91 | DHODH (0.51) | DHODHADORA1ADORA3 | |
| SCHEMBL4668512 | 0.87 | ADORA1 (0.41) | DHODHADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL4667038 | 0.85 | ADORA1 (0.39) | DHODHADORA1ADORA3 | |
| SCHEMBL14600460 | 0.84 | DHODH (0.51) | DHODHADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL14600455 | 0.78 | DHODH (0.47) | DHODHADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL14600994 | 0.77 | ADORA1 (0.46) | DHODHADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL14600459 | 0.76 | DHODH (0.49) | DHODHADORA1 | |
| SCHEMBL14600711 | 0.75 | DHODH (0.49) | DHODHADORA1ADORA3 | |
| SCHEMBL14600989 | 0.75 | DHODH (0.49) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |