SCHEMBL4667543

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4665711	0.95	EGFR (0.38)	EGFRKDRIKBKETBK1AURKA
	SCHEMBL4667471	0.94	EGFR (0.44)	EGFRKDRPDGFRBPDGFRAFLT1
	SCHEMBL4665785	0.93	EGFR (0.35)	EGFRKDRIKBKETBK1FLT1
	SCHEMBL4665829	0.93	EGFR (0.39)	EGFRKDRIKBKETBK1MEN1
	SCHEMBL4665833	0.92	KDR (0.41)	EGFRKDRAURKACDK1PDGFRB
	SCHEMBL4667481	0.90	PIK3R1 (0.42)	EGFRKDRIKBKETBK1AURKA
	SCHEMBL4663781	0.89	EGFR (0.39)	EGFRKDRIKBKETBK1FLT1
	SCHEMBL4665748	0.89	EGFR (0.42)	EGFRKDRIKBKETBK1PDGFRB
	SCHEMBL4665787	0.89	ABL1 (0.41)	EGFRKDRMETABL1BCR
	SCHEMBL4665873	0.87	EGFR (0.44)	EGFRKDRABL1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.