Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589461 | 1.00 | ADORA2A (0.61) | ADORA2AADORA3ADORA1 | |
| SCHEMBL591274 | 1.00 | ADORA2A (0.61) | ADORA2AADORA3ADORA1 | |
| SCHEMBL591275 | 1.00 | ADORA2A (0.61) | ADORA2AADORA3ADORA1 | |
| SCHEMBL2809727 | 0.94 | ADORA2A (0.54) | ADORA2AADORA3ADORA1 | |
| SCHEMBL590543 | 0.93 | ADORA2A (0.70) | ADORA2AADORA3ADORA1 | |
| SCHEMBL4669078 | 0.89 | ADORA2A (0.58) | ADORA2AADORA3ADORA1 | |
| SCHEMBL590402 | 0.89 | ADORA2A (0.58) | ADORA2AADORA3ADORA1 | |
| SCHEMBL590705 | 0.89 | ADORA2A (0.58) | ADORA2AADORA3ADORA1 | |
| SCHEMBL590704 | 0.89 | ADORA2A (0.58) | ADORA2AADORA3ADORA1 | |
| SCHEMBL598189 | 0.89 | ADORA2A (0.58) | ADORA2AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841768-B1 | PURINE DERIVATIVES ACTING AS A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2008-11-12 | — | — | EP | disclosed |