Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569836 | 0.86 | CHRM3 (0.36) | CHRM3NPC1RAB9ATAAR1ADRA2A | |
| SCHEMBL28298133 | 0.78 | TAAR1 (0.39) | CHRM3NPC1RAB9ATAAR1 | |
| SCHEMBL15066609 | 0.76 | TAAR1 (0.33) | CHRM3NPC1RAB9ATAAR1 | |
| Hydrochloric Acid SCHEMBL28704548 | 0.74 | TAAR1 (0.32) | CHRM3TAAR1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL28698065 | 0.74 | TAAR1 (0.32) | CHRM3TAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL22978805 | 0.74 | CHRM3 (0.36) | CHRM3NPC1RAB9ATAAR1 | |
| SCHEMBL27798200 | 0.74 | TAAR1 (0.45) | TAAR1 | |
| SCHEMBL1455173 | 0.74 | TAAR1 (0.45) | TAAR1 | |
| SCHEMBL1492956 | 0.72 | — | — | |
| SCHEMBL550395 | 0.69 | TAAR1 (0.50) | CHRM3NPC1RAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985612-A1 | Arymethylen substituted N-Acyl-gamma-aminoalcohols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-10-29 | — | — | EP | disclosed |