SCHEMBL4667797

SCHEMBL4667797

Fc1cccc(Cl)c1-c1c(Cl)nc2ncnn2c1N1C2CCC1CC2

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.39
TSHR P16473 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
PDE2A O00408 11/20 0.38
ALDH1A1 P00352 1/20 0.34
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4665970 0.92 PDE2A (0.37) GLATSHRNPSR1PDE2AALDH1A1
SCHEMBL4666636 0.86 PDE2A (0.38) GLATSHRNPSR1PDE2AALDH1A1
SCHEMBL4820822 0.85 TSHR (0.39) GLATSHRNPSR1PDE2AALDH1A1
SCHEMBL4666569 0.85 TSHR (0.41) GLATSHRNPSR1PDE2AALDH1A1
SCHEMBL4819468 0.84 TSHR (0.39) GLATSHRNPSR1PDE2AALDH1A1
SCHEMBL344327 0.84 TSHR (0.46) GLATSHRNPSR1PDE2AALDH1A1
SCHEMBL4817293 0.84 TSHR (0.40) GLATSHRNPSR1PDE2AALDH1A1
SCHEMBL4820465 0.83 PDE2A (0.39) GLATSHRNPSR1PDE2AALDH1A1
SCHEMBL8916197 0.83 PDE2A (0.39) GLATSHRNPSR1PDE2AALDH1A1
SCHEMBL4669016 0.82 PDE2A (0.35) GLATSHRNPSR1PDE2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1980150-A1 Fungicidal mixtures based on triazolopyrimidine compounds BASF SE (DE) 2008-10-15 EP claimed
EP-1980150-A1 Fungicidal mixtures based on triazolopyrimidine compounds BASF SE (DE) 2008-10-15 EP disclosed