SCHEMBL466800

SCHEMBL466800

C#C[C@@H](C)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL77308 1.00
SCHEMBL617335 1.00
Hydrochloric Acid SCHEMBL25230870 0.96
SCHEMBL11868098 0.86
Acetic Acid SCHEMBL4807645 0.83
SCHEMBL11869065 0.83
SCHEMBL17576 0.72
SCHEMBL9329374 0.72
SCHEMBL712154 0.72
SCHEMBL9329384 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 613 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114752634-A Preparation method of (R) 3-butyne-2-ol derivative 张邦成都生物医药科技有限公司 2022-07-15 CN claimed
US-7704705-B2 Esterases and their use for processes for kinetic resolution of butinolesters BASF SE (DE) 2010-04-27 US claimed
US-20090155865-A1 Esterases and their Use for Processes for Kinetic Resolution of Butinolesters BASF AKTIENGESELLSCHAFT (DE) 2009-06-18 US claimed
EP-1937809-A1 NEW ESTERASES AND THEIR USE FOR PROCESSES FOR KINETIC RESOLUTION OF BUTINOLESTERS BASF SE (DE) 2008-07-02 EP claimed
WO-2007042444-A1 NEW ESTERASES AND THEIR USE FOR PROCESSES FOR KINETIC RESOLUTION OF BUTINOLESTERS BASF SE (DE) 2007-04-19 WO claimed
US-12637438-B2 Protoporphyrinogen oxidase inhibitors ENKO CHEM, INC. (US) 2026-05-26 US disclosed
EP-4743457-A1 INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 FOR THERAPEUTIC USE 4M THERAPEUTICS INC. (US) 2026-05-20 EP disclosed
US-12623988-B2 Scaleable preparation of polyketides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-12 US disclosed
EP-4711368-A1 AZEPINE COMPOUND, AND COMPOSITION AND USE THEREOF CHENGDU MFS PHARMA. CO., LTD. (CN) 2026-03-18 EP disclosed
US-20260042780-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS INTELLIKINE LLC (US) 2026-02-12 US disclosed
US-20260042759-A1 INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI HANSOH BIOMEDICAL CO LTD (CN) 2026-02-12 US disclosed
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed
EP-0726897-A1 PROCESS FOR THE PREPARATION OF N-4- (SUBSTITUTED PHENYL)ALKYLTHIENYL]-, AND N-4- (SUBSTITUTED PHENYL)ALKYLFURYL]BUT-3-YN-2-YL]-N-HYDROXYUREA COMPOUNDS Abbott Laboratories (US) 1996-08-21 EP disclosed
EP-0685468-A1 Pyrazine and quinoxaline derivatives and their use as anti-ulcer agents Mochida Pharmaceutical Co., Ltd. (JP) 1995-12-06 EP disclosed
EP-0652864-A1 HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1995-05-17 EP disclosed
WO-1995012589-A1 PROCESS FOR THE PREPARATION OF N-4-[(SUBSTITUTED PHENYL)ALKYLTHIENYL]-, AND N-4-[(SUBSTITUTED PHENYL)ALKYLFURYL]BUT-3-YN-2-YL]-N-HYDROXYUREA COMPOUNDS ABBOTT LABORATORIES (US) 1995-05-11 WO disclosed
WO-1994002448-A1 HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1994-02-03 WO disclosed
EP-0384594-B1 Anti-inflammatory aryl derivatives WELLCOME FOUND (GB) 1993-10-27 EP disclosed
EP-0384594-A1 Anti-inflammatory aryl derivatives THE WELLCOME FOUNDATION LIMITED (GB) 1990-08-29 EP disclosed
EP-0351214-A1 Anti-inflammatory aryl derivatives THE WELLCOME FOUNDATION LIMITED (GB) 1990-01-17 EP disclosed