Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 8/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665974 | 0.94 | PDE2A (0.39) | PDE2AGLATSHRNPSR1ALDH1A1 | |
| SCHEMBL4666613 | 0.93 | PDE2A (0.39) | PDE2AGLATSHRNPSR1ALDH1A1 | |
| SCHEMBL4666576 | 0.87 | PDE2A (0.40) | PDE2AGLATSHRNPSR1ALDH1A1 | |
| SCHEMBL4820465 | 0.85 | PDE2A (0.39) | PDE2AGLATSHRNPSR1ALDH1A1 | |
| SCHEMBL8916197 | 0.85 | PDE2A (0.39) | PDE2AGLATSHRNPSR1ALDH1A1 | |
| SCHEMBL344327 | 0.84 | TSHR (0.46) | PDE2AGLATSHRNPSR1ALDH1A1 | |
| SCHEMBL4817293 | 0.84 | TSHR (0.40) | PDE2AGLATSHRNPSR1ALDH1A1 | |
| SCHEMBL5183058 | 0.84 | PDE2A (0.37) | PDE2AGLATSHRNPSR1ALDH1A1 | |
| SCHEMBL4818887 | 0.83 | TSHR (0.37) | PDE2AGLATSHRNPSR1ALDH1A1 | |
| SCHEMBL4810483 | 0.83 | TSHR (0.48) | PDE2AGLATSHRNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1980150-A1 | Fungicidal mixtures based on triazolopyrimidine compounds | BASF SE (DE) | 2008-10-15 | — | — | EP | disclosed |
| WO-2006100038-A1 | TRIAZOLOPYRIMIDINE DERIVATIVES USEFUL AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-09-28 | — | — | WO | disclosed |