Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668564 | 1.00 | CA1 (0.51) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL6708257 | 0.82 | MIF (0.61) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL2470556 | 0.82 | ESR1 (0.47) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL15547203 | 0.82 | BACE1 (0.44) | MIFKDM4EALDH1A1GAAMAPT | |
| SCHEMBL6072850 | 0.82 | MIF (0.41) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL2470558 | 0.82 | ESR1 (0.47) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL6708260 | 0.82 | MIF (0.61) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL6072860 | 0.82 | MIF (0.41) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL11306935 | 0.80 | EGFR (0.41) | MIFAKR1C3KDM4EMEN1ALDH1A1 | |
| SCHEMBL5386165 | 0.79 | FFAR1 (0.39) | CA1CA2NFKB1CA4MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7422855-B2 | Multiplexing assays for analyte detection | PERKINELMER LAS, INC. (US) | 2008-09-09 | — | — | US | disclosed |
| EP-1774033-A4 | MULTIPLEXING ASSAYS FOR ANALYTE DETECTION | PERKINELMER LAS INC (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1774033-A2 | MULTIPLEXING ASSAYS FOR ANALYTE DETECTION | PerkinElmer LAS, Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| US-20060003366-A1 | Multiplexing assays for analyte detection | PERKINELMER LAS, INC. | 2006-01-05 | — | — | US | disclosed |
| WO-2005123959-A2 | MULTIPLEXING ASSAYS FOR ANALYTE DETECTION | PERKINELMER LAS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |