SCHEMBL4668680

SCHEMBL4668680

CCOC(=O)C1C2CCC(C2)C1NC(=O)c1nn(-c2ccc(F)cc2F)c2c1CCC2Cc1cccc(F)c1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.43
CNR1 P21554 9/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3089681 1.00 CNR2 (0.43) CNR2CNR1
SCHEMBL10080074 1.00 CNR2 (0.43) CNR2CNR1
SCHEMBL176507 0.95 CNR2 (0.42) CNR2CNR1
SCHEMBL3893139 0.92 CNR2 (0.40) CNR2CNR1
SCHEMBL4708927 0.92 CNR2 (0.40) CNR2CNR1
SCHEMBL646121 0.90 CNR2 (0.46) CNR2CNR1
SCHEMBL176429 0.89 CNR2 (0.43) CNR2CNR1
SCHEMBL3469098 0.86 CNR2 (0.40) CNR2CNR1
SCHEMBL176450 0.86 CNR2 (0.40) CNR2CNR1
SCHEMBL4208017 0.85 CNR2 (0.45) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937646-A1 TETRAHYDRO-CYCLOPENTYL PYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2008-07-02 EP disclosed
WO-2007035945-A1 TETRAHYDRO-CYCLOPENTYL PYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2007-03-29 WO disclosed