SCHEMBL4668722

SCHEMBL4668722

O=S(=O)(O)c1[c]c(S(=O)(=O)O)c2ccccc2c1S(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TTR P02766 1/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
DAPK1 P53355 1/20 0.31
NAPRT Q6XQN6 1/20 0.31
MPL P40238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6631675 0.81 CYP2D6 (0.38) CYP2D6TSHRSMN1; SMN2TTRKDM4E
SCHEMBL6631428 0.78 CYP2D6 (0.39) CYP2D6TSHRSMN1; SMN2KDM4EPOLB
SCHEMBL1193834 0.78 CYP2D6 (0.43) CYP2D6TSHRSMN1; SMN2POLBTDP1
SCHEMBL14879315 0.78 TSHR (0.50) CYP2D6TSHRSMN1; SMN2TTRKDM4E
SCHEMBL2524546 0.75 TSHR (0.48) CYP2D6TSHRSMN1; SMN2TTRKDM4E
SCHEMBL6633106 0.74 CYP2D6 (0.43) CYP2D6TSHRSMN1; SMN2KDM4ETDP1
Hydrochloric Acid SCHEMBL11755878 0.73 TSHR (0.46) CYP2D6TSHRSMN1; SMN2TTRKDM4E
SCHEMBL6630646 0.73 CYP2D6 (0.45) CYP2D6TSHRSMN1; SMN2TTRKDM4E
SCHEMBL11805461 0.73 CYP2D6 (0.42) CYP2D6TSHRSMN1; SMN2TTRKDM4E
SCHEMBL7543033 0.72 CYP2D6 (0.51) CYP2D6TSHRSMN1; SMN2TTRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7381256-B2 Mixtures of fiber-reactive azo dyes, their production and their use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-06-03 US claimed
US-20070209540-A1 Mixtures Of Fiber-Reactive Azo Dyes, Their Production And Their Use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2007-09-13 US claimed
EP-1737915-A1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2007-01-03 EP claimed
WO-2005100485-A1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-10-27 WO claimed
EP-0972810-A1 Mixtures of reactive dyes and their use for dyeing material containing hydroxy and/or carbonamide groups DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-01-19 EP claimed
EP-0694053-B1 WATER-SOLUBLE FIBER-REACTIVE DYES, PROCESS FOR PRODUCING THE SAME AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO (DE) 1998-07-22 EP claimed
EP-0694053-A1 WATER-SOLUBLE FIBER-REACTIVE DYES, PROCESS FOR PRODUCING THE SAME AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-31 EP claimed
WO-1994024214-A1 WATER-SOLUBLE FIBER-REACTIVE DYES, PROCESS FOR PRODUCING THE SAME AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-27 WO claimed
EP-0196536-B1 WATER SOLUBLE AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-18 EP claimed
US-4725674-A COLORFASTNESS HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-16 US claimed
US-7381256-B2 Mixtures of fiber-reactive azo dyes, their production and their use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-06-03 US disclosed
EP-1666540-B1 Mixtures of fibre-reactive azo dyes, process for their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-03-26 EP disclosed
US-20070209540-A1 Mixtures Of Fiber-Reactive Azo Dyes, Their Production And Their Use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2007-09-13 US disclosed
EP-1737915-A1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2007-01-03 EP disclosed
US-20060117500-A1 Mixtures of fiber-reactive azo dyes, production thereof and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2006-06-08 US disclosed
EP-0624630-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-17 EP disclosed
WO-1994024214-A1 WATER-SOLUBLE FIBER-REACTIVE DYES, PROCESS FOR PRODUCING THE SAME AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-27 WO disclosed
US-5003053-A Water-soluble monoazo compounds containing a p-aminophenylamino- and chloro- or fluoro-substituted triazinylamino group and a fiber-reactive group selected from the vinylsulfone series, suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-26 US disclosed
US-4725674-A COLORFASTNESS HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-16 US disclosed
US-4329282-A Fluoro-triazine-containing fibre-reactive disazo dyestuffs BAYER AKTEINGESELLSCHAFT (DE) 1982-05-11 US disclosed