Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 4/20 | 0.55 |
| ▸ | CES1 | P23141 | 4/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466576 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1FAAH | |
| SCHEMBL14278987 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1FAAH | |
| SCHEMBL466777 | 1.00 | — | — | |
| SCHEMBL19369665 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1FAAH | |
| SCHEMBL10052558 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1FAAH | |
| SCHEMBL23221953 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1FAAH | |
| SCHEMBL467045 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1FAAH | |
| SCHEMBL20055685 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1FAAH | |
| SCHEMBL22765909 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1FAAH | |
| SCHEMBL466645 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877857-B2 | Polar group-containing copolymer, rubber composition and studless tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2014-11-04 | — | — | US | disclosed |
| EP-2404944-B1 | POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE | SUMITOMO RUBBER IND (JP) | 2014-05-14 | — | — | EP | disclosed |
| US-20120095153-A1 | POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| EP-2404944-A1 | POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2012-01-11 | — | — | EP | disclosed |
| EP-1881003-A1 | COMPOUND HAVING AMINO ACID RESIDUE OR PEPTIDE RESIDUE AND PROCESS FOR PRODUCING THE SAME | JAPAN CROWN CORK CO. LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |