Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.85 |
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.72 |
| ▸ | USP2 | O75604 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | HBB | P68871 | 1/20 | 0.67 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669058 | 1.00 | CDC25B (0.85) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4669372 | 0.92 | CDC25B (1.00) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4669374 | 0.92 | CDC25B (1.00) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4667578 | 0.91 | CDC25B (0.81) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4667576 | 0.91 | CDC25B (0.81) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4668210 | 0.90 | CDC25B (0.93) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4668214 | 0.90 | CDC25B (0.93) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4670252 | 0.88 | CDC25B (0.84) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4670253 | 0.88 | CDC25B (0.84) | CDC25BMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL14001085 | 0.88 | CDC25B (0.67) | CDC25BMEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2000140-A1 | Use of derivatives of 3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine or of 3-oxo-2,3-dihydro-5H-imidazolo[3,2-a]pyrimidine for the preparation of pharmaceutical compositions intended for the treatment of cancer | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-12-10 | — | — | EP | disclosed |